From the CD11b+ population, we can distinguish four subsets: (1) inflammatory monocytes defined as CD11b+ MHC (Major histocompatibility complex II)II− Ly6Chi; (2) immature macrophages defined as CD11b+ MHCIIhi Ly6Chi; (3) M1-like tumor-associated macrophages defined as CD11b+MHCIIhi Ly6C−; and (4) M2-like tumor-associated macrophages defined as CD11b+ MHCII− Ly6C−. The gene discussed is ITGAM; the disease is neoplasm.