SLC16A1 and amyotrophic lateral sclerosis: In addition, we gave insight into the monocarboxylate transporters 1 (MCT1/Slc16a1) in the BBB, sodium-coupled monocarboxylate transporters (SMCT1/Slc5a7) in ALS for the transport of acidic drugs such as 4-phenylbutyrate (PBA), organic cationic transporters (OCTN1/Slc22a4 and OCTN2/Slc22a5) for the transport of carnitine in ALS cell lines, and OCTN2 for the transport of acetyl-l-carnitine (ALCAR) in TR-BBB cells.