The overexpression of IL-8 is present in different types of cancer, including multiple myeloma, hepatocarcinoma, chronic lymphocytic leukemia [33,34,35,36,37] melanoma, colon carcinoma, pancreatic cell lines [33,34,35,36,37,38], and lung cancer [39]. The gene discussed is CXCL8; the disease is plasma cell myeloma.