Moreover, the analyzed genes that code for the different sodium/glucose transporters, potential targets of the SGLT2i, including SLC5A1 (SGLT1 protein) and SLC5A2 (SGLT2 protein), were detected in the human hearts of patients with HF and CNT individuals, but we did not observe statistically significant differences in the expression between both groups (Figure 1E). This evidence concerns the gene SLC5A1 and hydrops fetalis.