HPX and coronary artery disorder: HDL enriched with apoC-II, apoC-III, fibrinogen, Hx, SAA, and transferrin and depleted in apoJ, apoC-I, PON-1, C3, apoA-IV, PLTP, AAG, B2M, apoE and apoM was found in diabetic patients in a study by Cardner et al. However, according to this study, the role of specific HDL-proteomic alternations in coronary atherosclerosis development is not clear, mainly when considering the different remodelling pattern observed in CAD patients, although they have some similarities like HDL deprivation of apoA-IV and enrichment with pulmonary surfactant protein B and SAA [321].