APOA1 and systemic lupus erythematosus: Besides that, other studies found also reduced apoA-I and increased apoE content in HDL [339] and in serum of SLE patients, decreased PON1 [342], Gpx-3 activities [362,363,364] and increased Lp-PLA2 [328], sPLA2 [379] and CETP activities [342].