PON1 and chronic kidney disease: However, compared to a study by Mangé et al., in which authors applied isobaric tags for relative and absolute quantitation (iTRAQ) labelling and nanoflow liquid chromatography-mass spectrometry analysis, some inconsistencies and differences could be found, such as increased apoA-II, apoC-I, LCAT, apoM, PON1 and decreased fibrinogen, apoJ, transferrin, Hp, Hx, α2M in CKD [336].