MRC1 and cancer: In this paper, two focuses on solving the problem of bacterial resistance are considered: (i) the addressed delivery of fluoroquinolones to macrophages by targeting mannose receptors CD206 and (ii) the selective effect on bacteria (and in the future on cancer cells) due to adjuvant-increased penetration of drugs and inhibition of efflux and, as a consequence, accumulation of drugs in the area of pathogens localization.