A total of 33 studies analyzed VEGF, and 22 found increased levels of VEGF in patients with dengue, most of them severe dengue, compared with nonsevere dengue and/or healthy controls [12,13,14,15,16,17,18,19,20,21,22,23,24,25,26,27,28,29,30,31,32,33], including 5 studies in children only [16,17,21,26,27]. This evidence concerns the gene VEGFA and dengue disease.