For this purpose, we analysed the levels of selected cytokines in the tears of COVID-19 patients and found positive correlations between tear fluid IgA levels and the TNF-α (Rs = +0.23, p = 0.002), IL-1β (Rs = +0.25, p < 0.001), IL-2 (Rs = +0.20, p = 0.007), IL-4 (Rs = +0.16, p = 0.04), IL-5 (Rs = +0.36, p < 0.001), IL-6 (Rs = +0.32, p < 0.001), IL-8 (Rs = +0.31, p < 0.001), VEGF (Rs = +0.25, p < 0.001) and GM-CSF (Rs = +0.27, p < 0.001) concentrations in tears (Figure 3a–i). This evidence concerns the gene CSF2 and COVID-19.