INS and Insulin resistance: Consistently, previous studies showed that blood levels of long-chain n-3 PUFA were negatively correlated with hemoglobin A1c (HbA1c), levels of insulin, and homeostatic model assessment for insulin resistance (HOMA-IR) in Australian, Chinese, Korean, New Zealand, and Taiwanese adults with or without T2D, suggesting that long-chain n-3 PUFA could have a beneficial role in the risk of T2D [12,13,14,15,16].