These fatty acids may exert cardioprotective effects, mainly by reducing ventricular fibrillation, heart rate and platelet aggregation through various mechanisms, including improved synthesis of eicosanoids [49,50] and inhibition of the NF-kB pathway by acting on PPAR-gamma and certain G-protein-coupled receptors in macrophages and adipocytes, thus reducing the production of inflammatory cytokines [51]. Here, NFKB1 is linked to ventricular fibrillation.