AKT1 and cancer: On the other hand, the enriched pathways for carcinogenesis and cell proliferation, such as several pathways in cancer, Hippo signalling pathway, proteoglycan in cancer, cell cycle, Rap1 signalling pathway, viral carcinogenesis, MAPK signalling pathway, PI3k-Akt signalling pathway, Ras signalling pathway and TGF-beta signalling pathway were significantly downregulated.