To assess the effect of 8 weeks dietary supplementation with cRG-I on natural killer cell activity before the RV16 infection, expression of CD107a and cytotoxic activity were measured on d-55 and d-1 following ex vivo incubation of PBMC as a function of exogenous IL-2 in the presence of K562 target cells. The gene discussed is LAMP1; the disease is infection.