ERBB2 and cancer: Similarly, Dong et al. developed a formulation containing SPIONs, DOX, and Her2 GPDH (human epidermal growth factor receptor 2 glycine-aspartic acid-proline-histidine) as a theranostic agent, which was composed of perfluorooctyl bromide for bimodal US/MRI purposes and provided synergistic photodynamic therapy for Her2-positive cancer cells.