GCG and inflammatory bowel disease: Intraperitoneal administration of sterically stabilized phospholipid micelles coated with GLP-1 (GLP-1-SSM) for seven days in C57BL/6J mice with DSS-induced colitis resulted in decreased body weight loss and partially attenuated the diarrheal phenotype This treatment also downregulated the expression of the pro-inflammatory cytokine IL-1 β as well as prevented the depletion of the chloride anion exchanger DRA, which are both crucial for reducing diarrhea caused by IBD [127].