Moreover, the expression of nine AMPs of T. molitor (Tm-Tenecin1, Tm-Tenecin2, Tm-Tenecin4, Tm-Defensin2, Tm-Coleoptericin1, Tm-Coleoptericin2, Tm-Attacin1a, Tm-Attacin1b, and Tm-Attacin2) was significantly downregulated in Gram-negative infected knockdown larvae, while C. albicans challenge showed moderate expression of two AMPs (Tm-Defensin2 and Tm-Attacin2), suggesting possible involvement of Tm-IMD in AMP regulation against fungal infection. This evidence concerns the gene ADSL and fungal infectious disease.