After 1 h of infection, CCL2, CSF2, CXCL10, IFNB1, IL6, CXCL8, NFKBIA, TLR4, and TNF were upregulated, whereas CD14, IL12A, LY96, and TLR9 were downregulated (Figure 3A, left panel). The gene discussed is IL6; the disease is infection.