Physiological hyperbilirubinemia was assessed by measuring serum bilirubin concentrations in mice treated with CH, UGT1A1 antisense oligonucleotide, CsA, CsA + CH, and CsA + UGT1A1 antisense oligonucleotide (Figure 1). Here, UGT1A1 is linked to Hyperbilirubinemia.