CXCL8 and esophageal squamous cell carcinoma: The serum anti-CXCL8 autoantibody level in the ESCC group was, obviously, higher than that in the normal control group (p < 0.05) (Figure 4E); besides, the AUC value of anti-CXCL8 autoantibody was as high as 0.739 (95%CI: 0.692–0.787) and anti-CXCL8 autoantibody could distinguish 44.3% of ESCC patients at the specificity of 81.4% (Figure 4F).