In addition, the highest AUC value in SII combined diagnosis of HF comes from LMR combined with WMR (0.815, 95% CI 0.752–0.868), and the highest AUC value in SII combined with NT-proBNP diagnosis of HF is from LMR combined with NT-proBNP (0.841, 95% CI 0.778–0.892) (Table 7), and there were no significant differences in AUC between LMR and NT-proBNP/LMR combined with WMR (Table 8, Figure 2). This evidence concerns the gene NPPB and hydrops fetalis.