FOXD3 and neoplasm: The research also indicated that after 36 days of therapy, the tumours’ transcriptomes showed downregulation of stem-cell-related genes such as aldehyde dehydrogenase 1A1 (ALDH1A1), NANOG, GDF3, and the embryonic pluripotency-maintaining transcription factor Forkhead box D3 (FOXD3) [55].