Similarly, various other biomaterial coatings, e.g., Bioglass [44], silk sericin [45], LPS [52], Chitosan [48], IL-4 [53], Zinc [42], GPTMS [50], wound-healing peptides [54], aspirin [55] and anti-osteoporosis drugs [51], showed functionalization of the surface while maintaining the underlying topography (Table 5). Here, IL4 is linked to osteoporosis.