Investigating the adipocytokine signaling pathway MALT lymphoma showed the strongest expression of TNFR1, mTOR, AKT1 (p < 0.0079, FDR p < 0.0192), SOCS3 (p < 0.009, FDR p < 0.019) and STAT3 (p < 0.0025, FDR p < 0.0128), followed by NSOI showing a slight upregulation of mTOR and AKT compared to overall downregulation of compounds in IgG4-ROD (Figure 6). The gene discussed is STAT3; the disease is MALT lymphoma.