Disturbances in PPAR signaling have been associated with ARVC [10], and several studies utilizing ARVC induced pluripotent stem cell (iPSC) derived myocytes have employed pro-adipogenic factors, including PPAR agonists, to coax lipogenesis and calcium dysregulation in myocytes [11,12]. Here, PPARA is linked to arrhythmogenic right ventricular cardiomyopathy.