Abnormal growth of fibroblasts or hypertrophic scar tissue (keloids), or inflammatory factors over-expression, such as bFGF, TGF-β, PDGF, EGF, and CTGF in Dupuytren’s disease, can be found at the basis of the onset of these disorders [23,24]. This evidence concerns the gene FGF2 and Dupuytren Contracture.