Highly expressed LINC00963 causes BC cells to enhance radioresistance; its silencing results in an increase of radiosensitivity (restrains cell proliferation, impairs colony formation and tumor growth, arrest cells at the G0/G1 phase, stimulates apoptosis); LINC00963 induced radiosensitivity through the miR-324-3p/ACK1 axis. The gene discussed is LINC00963; the disease is breast cancer.