CRP and clostridium difficile infection: Until now, a series of typical risk factors for a more severe and complicated course of CDI have been identified, such as age ≥ 80 years, white cell count of <4 or ≥20 × 109/L, rise in serum creatinine (1.5-fold higher than the premorbid level, or absolute value of 1.5 mg/dL), increase in blood urea nitrogen (>7 mmol/L), and C-reactive protein levels ≥ 150 mg/L [3,4,5,6,7,8,9,10,16].