CLEC7A and infection: In addition, HSPCs have been described as expressing functional pattern recognition receptors (PRRs) on their surface, such as Toll-like receptors (TLR), including mainly TLR2 and TLR4, and C-like lectin receptors such as Dectin-1, among others [5,6], which are directly involved in the recognition of pathogens and the activation of the signaling pathways involved in the induction of proliferation and differentiation to macrophages during infection [3].