In the dynamic death curve at an MOI of 100:1, the emergence of PI-positive cells was delayed by the caspase-1 inhibitor in E. faecalis-infected RAW 264.7 cells and the number of PI-positive cells was significantly lower with the inhibitor YVAD than without the inhibitor YVAD at the same time point of infection. The gene discussed is CASP1; the disease is infection.