HSP90B2P and neoplasm: Some recent publications related high temperatures (>41.4 °C) to lower survival rates [14], and other studies related these findings to the synthesis of heat shock proteins (HSP) inside tumor cells, which ultimately protected the tumor cells (“thermotolerance”) by reducing the apoptosis generated by the chemotherapeutic drugs or selecting the subpopulations of tumor cells that were most resistant to the administered chemotherapy [50].