On admission patients with AKI had a higher creatinine level (1.3 mg/dL vs. 1.1 mg/dL p < 0.001), CRP (9.3 mg/L vs. 3.8 mg/L p < 0.001) and CPK (918 U/L vs. 776 U/L p < 0.001), but lower Hb (13.6 mg/dL vs. 14.4 mg/dL a long time to reperfusion (232.5 min vs. 165 min, p = 0.001), and the proportion of hemodynamically unstable patients was higher (16.9% vs. 2.2%, p < 0.001), they had a higher proportion of multiple vessel disease (more than two stenotic vessels 63.5% vs. 54.7% p = 0.008) and their EF after PCI was lower (45% vs. 50%, p < 0.001). The gene discussed is PIK3C2A; the disease is acute kidney injury.