REN and hydrops fetalis: The recent treatment strategies for HF patients are pharmacological therapies such as diuretics, beta blockers, renin–angiotensin system inhibition with Angiotensin Converting Enzyme Inhibitors (ACEi) or Angiotensin (II) receptor blockers (ARB) or Angiotensin Receptor-Neprilysin Inhibitor (ARNi), device therapies, and interventional therapies [27].