LPA and atherosclerosis: The equivalent to this 20 mg/week formulation was chosen for the phase III cardiovascular outcomes trial with pelacarsen, Lp(a) HORIZON, which is currently underway and studying the impact of 80 mg/month of pelacarsen vs. placebo on rates of recurrent ASCVD events in a secondary prevention population with baseline elevated Lp(a) (NCT04023552).