GSK3B and Alzheimer disease: We found that lateral ventricle injection of GSK3β inhibitor caused significant increases in the mean frequency (t1,28 = 3.168, p = 0.004; Figure 6B) and amplitude (t1,28 = 4.8887, p < 0.001; Figure 6C) of mEPSCs in 3 × Tg-AD mice.