In addition, hub genes such as RPS6, RPL34, SRP9, HNRNPA1, HNRNPM, SRRT, EIF5A, NONO, and PTBP1 were significantly up or downregulated in resistant breast cancer patients but not significant as prognostic biomarkers, also reported being involved in cancer progression. Here, PTBP1 is linked to breast carcinoma.