In addition, hub genes such as RPS6, RPL34, SRP9, HNRNPA1, HNRNPM, SRRT, EIF5A, NONO, and PTBP1 were significantly up or downregulated in resistant breast cancer patients but not significant as prognostic biomarkers, also reported being involved in cancer progression. The gene discussed is RPS6; the disease is breast carcinoma.