USP48 and ciliopathy: We selected ARL3 and UNC119a, among USP48 interactors in the retinal proteome, for further work due to several reasons: (1) mutations in UNC119a and ARL3 cause retinal dystrophy and, in the case of the latter, also a syndromic ciliopathy; and (2) both proteins are involved in the delivery of lipidated proteins to the photoreceptor OS, a pathway known as lipidated protein intraflagellar transport (LIFT).