In addition, Kumari et al. suggested that KC may act as an inhibitor for the main protease of SARS-CoV-2 and falcipain-2 involved in SARS-CoV-2 replication as well as ACE2 receptor binding through in silico molecular docking analysis [29], indicating that KC may be effective against COVID-19 by blocking SARS-CoV-2 entry via ACE2 receptor binding and inhibiting SARS-CoV-2 replication. This evidence concerns the gene CALCA and COVID-19.