18F-DPA-714 uptake is doubled in the presence of TSPO expressing DIPG cells, as highlighted by the significant rise of the pons to striatum AUC ratios of the tumor-bearing rats (AUCr = 2.03 ± 0.22 for tumor-bearing rats versus 1.55 ± 0.24 for sham rats; p-value = 0.02) (Figure 3B). The gene discussed is TSPO; the disease is neoplasm.