In that comparison, most contrasting changes have been shown by LDL-2 and -3 subfractions cholesterol levels, LDL-3 subfraction Apo-B100 apolipoproteins amount (L3AB) and statistically insignificant HDL-1 subfraction Apo-A2 apolipoprotein variables to be higher in AD. Here, APOA2 is linked to Alzheimer disease.