A systematic review of the role of DNA methylation in modifying blood pressure showed that lower methylation levels of SULF1 (sulfate endosulfatase), EHMT2 (Euchromatic Histone Lysine Methyltransferase 2), and SKOR2 (SKI Family Transcriptional Corepressor 2) were associated with hypertension. The gene discussed is SKOR2; the disease is hypertensive disorder.