SIRT5 and epilepsy: Our work on multiple changes in glutarylation levels of proteins after seizures (Figure 1), and strong positive and negative correlations of these modifications in the brain proteins with the levels of glutaryl-CoA producer OADH and deglutarylase SIRT5 correspondingly (Figure 3), warrants further studies on the glutarylation system of the brain as a potential target in epilepsy treatment.