Single nucleotide polymorphisms (SNPs) of the NLRP1 gene are associated with different (auto)inflammatory diseases, which mainly affect the skin, including vitiligo, Addison’s disease, and NAIAD (NLRP1-associated autoinflammation with arthritis and dyskeratosis) [101,129,130,131]. The gene discussed is NLRP1; the disease is arthritic joint disease.