Gene expression levels of the lysosomal markers lysosome-associated membrane glycoprotein 1 (Lamp1) and Lamp2 remained unaltered, but we observed increased gene transcripts of the lysosomal cholesterol exporter Niemann-Pick disease type C1 (Npc1) in placentae of mice after HF/HCD feeding with and without GDM (Figure 3C). This evidence concerns the gene NPC1 and hydrops fetalis.