LEP and obesity due to melanocortin 4 receptor deficiency: Furthermore, the obesity statuses showed that leptin levels were significantly higher in obese individuals (19.91 ± 19.11) compared with non-obese individuals (p < 0.001); in non-obese women (10.19 ± 7.52) compared with non-obese men (p < 0.001); and in obese women (26.59 ± 21.54) compared with obese men (p < 0.001).