Significantly elevated numbers of IgD−CD38lowCD27+ class-switched B cells (Ctrl: 58 (52–64)%; Mildt2: 78 (73–80)%; Figure 1C) correlated with increased concentrations of α-Spike-Ab after 7 days (t2) after the onset of infection (t2, p = 0.01, r = 0.59). This evidence concerns the gene CHMP5 and infection.