In a murine lupus model, the inhibition of a multifunctional serine/threonine kinase, namely, calcium/calmodulin-dependent protein kinase IV (CaMK4), led to the decrease in CCR6 and CCL20 expression, as well as to the amelioration of glomerular injury, which highlighted the role of the CCR6/CCL20 axis in SLE [60]. The gene discussed is CCR6; the disease is systemic lupus erythematosus.