MiR-454 impaired the expression of neural precursor cells, developmentally downregulated the 4-2 (NEDD4-2)/tropomyosin receptor kinase A (TRKA)/cAMP axis in cardiomyocytes injured by oxidative stress, and its expression was found to be downregulated in a rat HF model [99]. Here, NTRK1 is linked to hydrops fetalis.