In contrast, IFT20 has been shown to promote invasiveness and migration of osteoblastoma and colorectal cancer cells independently of the PC by promoting the reorientation of the Golgi complex toward the direction of migration, the anterograde Golgi transport and the GM130–AKAP450 interaction to nucleate Golgi-associated microtubules, suggesting a cell-specific role for IFT20 in this process [66,67]. The gene discussed is IFT20; the disease is Osteoblastoma.