For the glioma TCGA cohort, the risk score was calculated as follows: risk score = (0.6457 × PGAM5 expression) + (0.8062 × SQSTM1 expression) + (−0.4834 × ATG9A expression) + (−0.6285 × GABARAPL1 expression). The gene discussed is SQSTM1; the disease is central nervous system cancer.