In summary, after hepatic ischemia–reperfusion combined with partial resection injury in rats, ADSC-Exo administration inhibits the pyroptosis resulting from inflammatory responses, reduces liver injury, and promotes liver regeneration; related mechanisms may be through the inhibition of the NF-κB pathway and the activation of the Wnt/β-catenin pathway (Figure 8). This evidence concerns the gene NFKB1 and ischemia.