At the same time, a significant difference in the ratio of FL to Δ7 SMN transcripts was detected between SMA patients and healthy individuals (Figure 1c) (median FL/Δ7 ratios of SMN transcripts were 1.08 for healthy individuals, 0.95 for SMA carriers, and 0.85 for SMA patients). The gene discussed is SMN1; the disease is proximal spinal muscular atrophy.